More than 370 years ago the famous French mathematician Pierre de Fermat proposed to solve the following problem: to find a Pythagorean triples whose hypotenuse and the sum of the legs were squares, which, despite its simplicity, has been very difficult. Problems associated with its solution involved many mathematicians such as (Leonhard Euler, Joseph-Louis Lagrange, Ljnggren, Wacław Sierpiński and etc.) But in the end it did not reach solution. In our article, solution communicated to obtain the equations giving the required values all elements of the Pythagorean triples in positive integers (natural) are co-prime integers, and provides a second solution of this problem (the values of x, y, z of 45 digits), and some consequences.